Courses@CRG: CHROMOSOMAL CONFORMATION

The eukaryotic genome is non-randomly organized in a hierarchy of structures: chromosomes territories, which occupy preferential positions within the interphasic nucleus, are segmented into topological domains where loops between enhancer and promoters are favored. Such organization plays important roles in the processing of the genetic information including replication and gene transcription. The Chromosomal Conformation Course at CRG will provide an overview of different methods to study the three-dimensional organization of the genome. The participants will have the opportunity to learn how to perform Chromosome Conformation Capture (3C) experiments and to generate Hi-C samples as well as to learn the computational methods required to analyze such data. The course will be complemented by lectures of several internationally renowned researchers in the field that will touch different aspects of the 3D organization of genome.

The course will be divided in two practical sessions:

1. In the first session the participant will perform 3C and Hi-C experiment and will focus on the quality controls that are required prior to sequence the libraries.
2. The second session will be dedicated to the post-sequencing quality controls and the analysis of hi-C data through the use of a dedicated pipeline.

Organizers

François Le Dily, CRG, Spain

Miguel Beato, CRG, Spain

Gaetano Verde, IMIM, Spain

Davide Baù, CRG-CNAG, Spain

François Serra, CRG-CNAG, Spain

Speakers

Ivan Junier, Universite de Grenoble, France

Pia Cosma, CRG, Spain

Victor Corces, Emory University, USA

Guillaume Filion, CRG, Spain

Instructors

Gaetano Verde, IMIM, Spain

François Le Dily, CRG, Spain

Yasmina Cuartero, CRG-CNAG, Spain

François Serra, CRG-CNAG, Spain

Davide Baù, CRG-CNAG, Spain

Ralf Stadhouders, CRG, Spain

Target audience

This course is targeting junior researchers (PhD students, Postdocs, PIs) with interests in the Chromosome Conformation analysis and Nuclear Organization.

Duration

5 days: Starting on Monday April 3rd at 9 am and finishing on Friday April 7th at 5 pm.

Number of participants: 16

Registration fee: 500 Euros for academic researchers, 1000 Euros for industry (includes participation in workshop, all the necessary tools to follow the course, didactic material, coffee breaks, lunches, networking event).

Registration:
Only online registration is accepted

Registration Closes: 15th January 2017

Worldwide participants will be selected according to their CV and motivation letter submitted.

Selected Participants will be notified via email by the end of January 2017.

Venue

CRG – Centre for Genomic Regulation
Dr. Aiguader 88
08003 Barcelona, Spain
How to get to the CRG ?

Contact

Training
Dr. Aiguader 88
08003 Barcelona

Email training@crg.eu

Supported by:

 We acknowledge support from the Spanish ministry of Economy and Competitiveness,
“Centro de Excelencia Severo Ochoa 2013-2017”, SEV 2012-0208.