PRBB-CRG Sessions

31/10/202512:00MARIE CURIEPRBB-CRG SessionsKristen VerheyUniversity of Michigan Medical School"Dynamics and structural changes within the microtubule lattice"Host: Thomas SurreyAbstract:Microtubules are cytoskeletal filaments that self-assemble from the protein tubulin and are critical for a variety of important functions in eukaryotic cells, including cell mechanics, migration, and division. Much work in the field has focused on the dynamics at the ends of microtubules and specifically, how tubulin’s GTP binding and hydrolysis drives the addition and loss of tubulin subunits at the ends. However, an emerging idea in the field is that the structure...