The overarching goal of the proposal presented here is the use of massively parallel sequencing for the identification of novel genetic and epigene
Biological systems are robust to perturbations, with many genetic, stochastic and environmental challenges having no or little phenotypic consequen
Alternative splicing (AS) is the largest contributor to transcriptomic diversification in metazoans.
A major portion of the eukaryotic genome is occupied by DNA sequences whose transcripts do not code for proteins.
Alternative splicing of messenger RNA precursors is a prevalent form of gene regulation that greatly expands the coding capacity and regulatory opp
Engineering bacteria to deliver therapeutic agents or to present antigens for vaccination is an emerging area of research with great clinical poten
Organogensis is the process by which multiple different cell types grow, differentiate and interact with each other (both molecularly and physicall