NONAME1
Molecular regulators of GABAergic systems that underlie comorbidities in Down syndrome
Principal Investigator/s
Field / Programme
Systems and Synthetic Biology
Systems and Synthetic Biology
Summary
The objective of the proposed study is to identify molecular regulators of GABAergic systems that underlie comorbidities in DS. Its successful completion will identify the molecular regulators of the GABAergic system in the DS hippocampus and discover them as common contributors to the comorbidities between epilepsy and intellectual disability in DS. This knowledge will offer insights into the development of therapeutic treatments that target these DS-related conditions. The knowledge will also provide insights into other neurological disorders.
The objective of the proposed study is to identify molecular regulators of GABAergic systems that underlie comorbidities in DS. Its successful completion will identify the molecular regulators of the GABAergic system in the DS hippocampus and discover them as common contributors to the comorbidities between epilepsy and intellectual disability in DS. This knowledge will offer insights into the development of therapeutic treatments that target these DS-related conditions. The knowledge will also provide insights into other neurological disorders.
Start: 01/07/2024 End: 31/05/2029
Total Budget: $2.078.127,00
CRG Budget: $529.989,20
Funded by:
