OCEANIC
Restoring vision by integrating optic nerve organoids in retinitis pigmentosa rat visual circuity
Principal Investigator/s
Field / Programme
Systems and Synthetic Biology
Systems and Synthetic Biology
Summary
About 1 in 4000 people worldwide will go blind due to the loss of the retinal photoreceptors, which are the cells that convert light into electrical signals for transmission to the brain. Retinitis pigmentosa (RP) is the most common reason for blindness. There is currently no cure for late-stage retinal degenerations in which photoreceptors have already been lost. However, we are now focusing on the fact that a portion of the retina is still functional, even in blindness from RP. This project aims to create a novel regenerative therapy in which a synthetic retina will be connected to the remaining retina.
About 1 in 4000 people worldwide will go blind due to the loss of the retinal photoreceptors, which are the cells that convert light into electrical signals for transmission to the brain. Retinitis pigmentosa (RP) is the most common reason for blindness. There is currently no cure for late-stage retinal degenerations in which photoreceptors have already been lost. However, we are now focusing on the fact that a portion of the retina is still functional, even in blindness from RP. This project aims to create a novel regenerative therapy in which a synthetic retina will be connected to the remaining retina.
Start: 30/12/2024 End: 29/12/2027
Total Budget: 997.293,00
CRG Budget: 599.800,00
Partners
Funded by:
